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Clinical management and outcomes of HIV-positive patients newly diagnosed with prostate cancer: a single institution experience

Prostate Cancer and Prostatic Diseases volume 27, pages 144–146 (2024)Cite this article

Subjects

Abstract

Introduction

10-year outcomes in patients living with HIV who are diagnosed with prostate cancer are unknown.

Methods

52 patients living with HIV were diagnosed with prostate cancer. Disease-free survival stratified by clinical, pathologic, and HIV characteristics were examined.

Results

No difference in disease-free survival was observed based on prostate cancer treatment modality, CD4 count, or HIV viral load.

Conclusions

Prostate cancer outcomes in patients living with HIV are favorable irrespective of treatment modality.

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Fig. 1: Prostate cancer disease-free survival in 48 Men enrolled in the Johns Hopkins HIV Clinical Cohort, 1998-2019.

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Data availability

This dataset will be made available upon request to corresponding author.

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Funding

This study was funded by U01 DA036935, P30 AI094189, U01 AI069918, R01 CA250851, P30 CA006973. C Joshu was supported by RSG-18-147-01. F Pirsl was supported by the NCI Cancer Epidemiology, Prevention, and Control Grant (T32CA0093140). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Author information

Authors and Affiliations

  1. Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA

    Mark C. Markowski, Bryan Lau & Corinne E. Joshu

  2. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA

    Filip Pirsl, Bryan Lau & Corinne E. Joshu

  3. Department of Medicine, Division of Infectious Disease, Johns Hopkins School of Medicine, Baltimore, MD, USA

    Jeanne C. Keruly

  4. Department of Medicine, Division of General Internal Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA

    Geetanjali Chander, Richard D. Moore & Bryan Lau

Authors
  1. Mark C. Markowski
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  2. Filip Pirsl
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  3. Jeanne C. Keruly
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  4. Geetanjali Chander
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  5. Richard D. Moore
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  6. Bryan Lau
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  7. Corinne E. Joshu
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Contributions

MCM: Conceptualization, Methodology, Data Analysis, Writing and Editing, FP: Methodology, Data Analysis; JCK: Conceptualization, Manuscript Editing; GC: Conceptualization, Manuscript Editing; RDP: Conceptualization, Supervision, Manuscript Editing; BL: Data Analysis, Manuscript Editing; CEJ: Conceptualization, Formal Analysis, Funding Acquisition, Supervision, Manuscript Editing.

Corresponding author

Correspondence to Mark C. Markowski.

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The authors declare no competing interests.

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Markowski, M.C., Pirsl, F., Keruly, J.C. et al. Clinical management and outcomes of HIV-positive patients newly diagnosed with prostate cancer: a single institution experience. Prostate Cancer Prostatic Dis 27, 144–146 (2024). https://doi.org/10.1038/s41391-022-00586-7

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  • DOI: https://doi.org/10.1038/s41391-022-00586-7

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