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Association between maternal HIV disclosure and risk factors for perinatal transmission

Journal of Perinatology volume 38, pages 639–644 (2018)Cite this article

Subjects

Abstract

Objective

To determine whether maternal disclosure of HIV serostatus is associated with uptake of perinatal HIV transmission prevention interventions.

Study design

Retrospective cohort study of women living with HIV enrolled in a perinatal HIV clinic. Women who disclosed their HIV serostatus to sexual partner(s) prior to delivery were compared to non-disclosers. Multivariable logistic regression was performed.

Results

Of 209 women, 71.3% (N = 149) disclosed. Non-disclosers were more likely to attend <10 prenatal visits, demonstrated worse antiretroviral therapy adherence, required more time to achieve virologic suppression, and were less likely to have an undetectable viral load. On multivariable analyses, disclosure status did not remain associated with these factors. However, compared to non-disclosers, disclosers had lower odds of preterm delivery (OR: 0.43, 95% CI: 0.19–0.94) and greater odds of postpartum visit attendance (aOR: 5.10, 95% CI: 1.65–15.72).

Conclusions

Non-disclosure of HIV status to sexual partner(s) during pregnancy may be a risk factor for preterm birth and poorer postpartum visit attendance.

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Funding

LMY and ESM were supported by the NICHD K12 HD050121-11 and K12 HD050121-09, respectively.

Author information

Authors and Affiliations

  1. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Lynn M Yee, Patricia M Garcia & Emily S Miller

  2. Division of Infectious Diseases, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Donna V McGregor & Sarah H Sutton

  3. Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Emily S Miller

Authors
  1. Lynn M Yee
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  2. Donna V McGregor
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  3. Sarah H Sutton
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  4. Patricia M Garcia
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  5. Emily S Miller
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Corresponding author

Correspondence to Lynn M Yee.

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The authors declare that they have no conflict of interest.

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Yee, L.M., McGregor, D.V., Sutton, S.H. et al. Association between maternal HIV disclosure and risk factors for perinatal transmission. J Perinatol 38, 639–644 (2018). https://doi.org/10.1038/s41372-018-0066-2

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  • DOI: https://doi.org/10.1038/s41372-018-0066-2

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