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A Hec of a microtubule attachment

Nature Structural & Molecular Biology volume 14, pages 11–13 (2007)Cite this article

The central function of kinetochores is to grasp a dynamic microtubule. Structural, biochemical and cell biological approaches have converged to uncover a microtubule-binding activity within the Ndc80/HEC1 complex, providing a satisfying answer to a question that has puzzled biologists for the last century.

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Figure 1: Model for microtubule attachment by the kinetochore.

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  1. the Department of Biochemistry and Molecular Genetics, University of Virginia Medical School, Charlottesville, 22908, Virginia, USA

    Michael Emanuele, Daniel J Burke & P Todd Stukenberg

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  1. Michael Emanuele
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  2. Daniel J Burke
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  3. P Todd Stukenberg
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Emanuele, M., Burke, D. & Stukenberg, P. A Hec of a microtubule attachment. Nat Struct Mol Biol 14, 11–13 (2007). https://doi.org/10.1038/nsmb0107-11

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