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Stroke in 2011

Major advances across the spectrum of stroke care

Nature Reviews Neurology volume 8, pages 63–64 (2012)Cite this article

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Several pivotal clinical trials that could have a major impact on the care of patients with stroke were published in 2011. The studies cover a wide range of stroke-care aspects, including stroke prevention, imaging to select patients for thrombolysis, therapies for stroke recovery, and stroke registries to improve care quality.

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Figure 1: The 'stroke systems of care' model defines a spectrum of seven domains that cover all aspects of stroke care.

References

  1. Schwamm, L. H. et al. Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems. Circulation 111, 1078–1091 (2005).

    Article  PubMed  Google Scholar 

  2. Granger, C. B. et al. Apixaban versus warfarin in patients with atrial fibrillation. N. Engl. J. Med. 365, 981–992 (2011).

    Article  CAS  PubMed  Google Scholar 

  3. Diener, H.-C. et al. Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischemic attack or stroke. Lancet Neurol. 9, 1157–1163 (2010).

    Article  CAS  PubMed  Google Scholar 

  4. Patel, M. R. et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N. Engl. J. Med. 365, 883–891 (2011).

    Article  CAS  PubMed  Google Scholar 

  5. Chimowitz, M. I. et al. Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N. Engl. J. Med. 352, 1305–1316 (2005).

    Article  CAS  PubMed  Google Scholar 

  6. Chimowitz, M. I. et al. Stenting versus aggressive medical therapy for intracranial arterial stenosis. N. Engl. J. Med. 365, 993–1003 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Hacke, W. et al. Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion–diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study. Lancet Neurol. 8, 141–150 (2009).

    Article  CAS  PubMed  Google Scholar 

  8. Lansberg, M. G. et al. RAPID automated patient selection for reperfusion therapy: a pooled analysis of the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) and the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) study. Stroke 42, 1608–1614 (2011).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Chollet, F. et al. Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial. Lancet Neurol. 10, 123–130 (2011).

    Article  CAS  PubMed  Google Scholar 

  10. Reeves, M. J. et al. Representativeness of the Get With The Guidelines-Stroke Registry: comparison of patient and hospital characteristics among medicare beneficiaries hospitalized with ischemic stroke. Stroke http://dx.doi.org/10.1161/STROKEAHA.111.626978.

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  1. Department of Neurology-ACC 720, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, Boston, 02114, MA, USA

    Lee H. Schwamm

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  1. Lee H. Schwamm
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Schwamm, L. Major advances across the spectrum of stroke care. Nat Rev Neurol 8, 63–64 (2012). https://doi.org/10.1038/nrneurol.2011.225

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