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A complex role for adipose tissue macrophages

Nature Reviews Endocrinology volume 10, pages 193–194 (2014)Cite this article

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Increased infiltration of adipose tissue macrophages (ATMs) and their subsequent inflammatory effects are implicated in the development of insulin resistance among individuals with obesity. Interestingly, new data published in Cell Metabolism suggest that ATMs might also have important noninflammatory roles in lipid trafficking and its metabolic consequences.

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Figure 1: Recycling of lipids by ATMs.

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Authors and Affiliations

  1. Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, 48109, MI, USA

    Shannon M. Reilly & Alan R. Saltiel

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  1. Shannon M. Reilly
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  2. Alan R. Saltiel
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Correspondence to Alan R. Saltiel.

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The authors declare no competing financial interests.

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Reilly, S., Saltiel, A. A complex role for adipose tissue macrophages. Nat Rev Endocrinol 10, 193–194 (2014). https://doi.org/10.1038/nrendo.2014.12

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