Laminar neuronal density varies between cortical areas; thus, the developmental specification of areas and layers needs to be coordinated. AP2γ turns out to be an important regulator of upper layer development in occipital cortex.
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Waclaw, R., Campbell, K. Regional control of cortical lamination. Nat Neurosci 12, 1211–1212 (2009). https://doi.org/10.1038/nn1009-1211
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DOI: https://doi.org/10.1038/nn1009-1211