Some people seem to hold their liquor better than others, but are also more prone to becoming alcoholics. Altered function of the adenosine type 1 equilibrative nucleoside transporter (ENT1), which regulates the neurotransmitter adenosine, may be the reason.
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Melendez, R., Kalivas, P. Last call for adenosine transporters. Nat Neurosci 7, 795–796 (2004). https://doi.org/10.1038/nn0804-795
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DOI: https://doi.org/10.1038/nn0804-795
