Acupuncture entails stimulating discrete points on the body with needles to alleviate pain. A study in this issue finds that local activation of adenosine A1 receptors in mice contributes to the anti-nociceptive effects of acupuncture.
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Zylka, M. Needling adenosine receptors for pain relief. Nat Neurosci 13, 783–784 (2010). https://doi.org/10.1038/nn0710-783
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DOI: https://doi.org/10.1038/nn0710-783
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