Thermal profiling in combination with quantitative proteomics makes it possible to identify cellular membrane protein targets of small molecules.
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Leestemaker, Y., Ovaa, H. Hitting the target. Nat Methods 12, 1127–1128 (2015). https://doi.org/10.1038/nmeth.3660
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DOI: https://doi.org/10.1038/nmeth.3660