Using two independent methods, researchers show that in vivo–grown crystals of soluble proteins and of membrane proteins grown in the lipidic sponge phase can be analyzed by serial femtosecond crystallography on an X-ray free electron laser.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Katie Vicari
References
Koopmann, R. et al. Nat. Methods 9, 259–262 (2012).
Johansson, L.C. et al. Nat. Methods 9, 263–265 (2012).
Emma, P. et al. Nat. Photonics 4, 641–647 (2010).
Neutze, R. et al. Nature 406, 752–757 (2000).
Doye, J.P.K. & Poon, W.C.K. Curr. Opin. Colloid Interface Sci. 11, 40–46 (2006).
Fan, G.Y. et al. Microsc. Res. Tech. 34, 77–86 (1996).
DePonte, D.P. et al. J. Phys. D. Appl. Phys. 41, 195505 (2008).
Chapman, H.N. et al. Nature 470, 73–77 (2011).
Caffrey, M. Annu. Rev. Biophys. 38, 29–51 (2009).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Moffat, K. Small is beautiful. Nat Methods 9, 242–243 (2012). https://doi.org/10.1038/nmeth.1895
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.1895
