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Aβ star: a light onto synaptic dysfunction?

Nature Medicine volume 12, pages 760–761 (2006)Cite this article

Learning and memory is impaired in a mouse model of Alzheimer disease. An Aβ 12-mer called Aβ* may be responsible for these cognitive deficits.

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Figure 1: Aβ*56, most likely a tetramer of Aβ trimers, is the prime candidate suspected of causing early memory deficits in a mouse model of Alzheimer disease4.

Kim Caesar

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Authors and Affiliations

  1. Department of Neurobiology, Pharmacology & Physiology,

    Seong-Hun Kim, Ya-Ping Tang & Sangram S Sisodia

  2. Department of Psychiatry, University of Chicago, Chicago, 60637, Illinois, USA

    Seong-Hun Kim, Ya-Ping Tang & Sangram S Sisodia

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  1. Seong-Hun Kim
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  2. Ya-Ping Tang
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  3. Sangram S Sisodia
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Kim, SH., Tang, YP. & Sisodia, S. Aβ star: a light onto synaptic dysfunction?. Nat Med 12, 760–761 (2006). https://doi.org/10.1038/nm0706-760

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