The nuclear hormone receptor LXR—best known for sensing cholesterol metabolites—also responds to glucose. The findings give LXR a central role in modulating the body's response to metabolic inputs.
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Rodgers, J., Puigserver, P. Receptor feasts on sugar and cholesterol. Nat Med 13, 128–129 (2007). https://doi.org/10.1038/nm0207-128
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DOI: https://doi.org/10.1038/nm0207-128