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Dendritic cells: a journey from laboratory to clinic

Dendritic cell–based vaccines have been rapidly transferred from the laboratory to the clinic. As the full potential of these cells has not yet been entirely exploited, many strategies could improve the immunogenicity of these vaccines.

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Figure 1: Vaccine-driven priming of antigen-specific T cells in the lymph node.

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Acknowledgements

We thank G. Schuler, P. Coulie, P. Romero, C. Smith and M. Palmowski for comments on this manuscript.

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Correspondence to Vincenzo Cerundolo.

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Cerundolo, V., Hermans, I. & Salio, M. Dendritic cells: a journey from laboratory to clinic. Nat Immunol 5, 7–10 (2004). https://doi.org/10.1038/ni0104-7

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