Abstract
Therapies that target molecular pathways do not provide uniform benefits for all patients at present. New transformative therapies for autoimmune and inflammatory diseases require greater molecular understanding of patient subsets and the ability to personalize targeted therapies for each subset.
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Acknowledgements
We thank J. Arron, E. Brown, J. Monroe, J. Settleman and M. Townsend for discussions, and A. Bruce for assistance in illustration.
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A.C.C. and T.W.B. are employees of Genentech.
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Chan, A., Behrens, T. Personalizing medicine for autoimmune and inflammatory diseases. Nat Immunol 14, 106–109 (2013). https://doi.org/10.1038/ni.2473
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DOI: https://doi.org/10.1038/ni.2473
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