Abstract
SEQUENCES of 5S rRNA have been published for five widely divergent organisms: Escherichia coli, Pseudomonas fluorescens, yeast, human KB carcinoma, and Xenopus laevis1–5. The question arises whether sequences for the ancestors of these organisms, represented by X, Y, and Z in Fig. 1, can be reconstructed to any degree of confidence; were this possible, statistical analysis of mutation types would become feasible. Such reconstructions are well known in protein studies6 and for tRNAs7, but they are somewhat more difficult for 5S rRNA.
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References
Brownlee, G. G., Sanger, F., and Barrell, B. G., J. molec. Biol., 34, 379 (1968).
DuBuy, B., and Weissman, S. M., J. biol. Chem., 246, 747 (1971).
Brownlee, G. G., Cartwright, E., McShane, T., and Williamson, R., FEBS Lett., 25, 8 (1972).
Forget, B. G., and Weissman, S. M., Science, N.Y., 158, 1695 (1967).
Hindley, J., and Page, S. M., FEBS Lett., 26, 157 (1972).
Dayhoff, M. O., Scient. Am., 221, 86 (1969).
Cedergren, R. J., Cordeau, J. R., and Robillard, P., J. theor. Biol., 37, 209 (1972).
Sankoff, D., Publ. Cent. Rech. Math., Technical report 262 (1973).
Vogel, F., J. mol. Evol., 1, 334 (1972).
Dayhoff, M. O., in Atlas of Protein Sequence and Structure, 5, 113, (Nat. Biomed. Res. Found., Washington, DC, 1972).
Watson, J. D., and Crick, F. H. C., Cold Spring Harb. Symp. quant. Biol., 18, 193 (1953).
Dayhoff, M. O., in Atlas of Protein Sequence and Structure, 5, 44, (Nat. Biomed. Res. Found., Washington, DC, 1972).
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SANKOFF, D., MOREL, C. & CEDERGREN, R. Evolution of 5S RNA and the Non-randomness of Base Replacement. Nature New Biology 245, 232–234 (1973). https://doi.org/10.1038/newbio245232a0
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DOI: https://doi.org/10.1038/newbio245232a0
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