This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Marson AG et al. (2007) The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalized and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet 369: 1016–1026
Mattson RH et al. (1985) A comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic–clonic seizures. N Engl J Med 313: 145–151
Mattson RH et al. (1992) Comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic–clonic seizures in adults. N Engl J Med 327: 765–771
Rowan AJ et al. (2005) New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. Neurology 64: 1868–1873
Brodie MJ et al. (1995) Double blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. UK Lamotrigine/Carbamazepine Monotherapy Trial Group. Lancet 345: 476–479
Gilliam FG et al. (2005) Epilepsy and common comorbidities: improving the outpatient epilepsy encounter. Epileptic Disord 7 (Suppl 1): S27–S33
Acknowledgements
The synopsis was written by Martina Habeck, Associate Editor, Nature Clinical Practice.
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The author has declared associations with Eisai (consultant, grant/research support), GlaxoSmithKline (speaker honoraria), Pfizer (consultant, speaker honoraria, grant/research support), and UCB Pharma (consultant, speaker honoraria, grant/research support).
Rights and permissions
About this article
Cite this article
Bazil, C. Are the first-line recommendations for antiepileptic drug therapy still valid?. Nat Rev Neurol 3, 484–485 (2007). https://doi.org/10.1038/ncpneuro0557
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/ncpneuro0557