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A glimpse of coated vesicle creation? Well almost!

Nature Cell Biology volume 4, pages E230–E232 (2002)Cite this article

The budding of a cargo-laden clathrin-coated pit (CP) from the plasma membrane (PM) during receptor-mediated endocytosis is a paradigm of vesicular transport. A recent study published in Nature Cell Biology helps us visualize the creation of the clathrin-coated vesicle, and the involvement of dynamin and actin as potential 'midwives' in the process. Still, it remains a matter of faith as to exactly when life begins for the coated vesicle.

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Figure 1: A time-line for fluorescence changes and the formation of endocytic structures.

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  1. the Deptartment of Microbiology and Immunology, Cellular Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, 19107, PA, USA

    Francesca Santini & James H. Keen

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  1. Francesca Santini
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  2. James H. Keen
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Santini, F., Keen, J. A glimpse of coated vesicle creation? Well almost!. Nat Cell Biol 4, E230–E232 (2002). https://doi.org/10.1038/ncb1002-e230

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