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A reader for centromeric chromatin

Nature Cell Biology volume 11, pages 793–795 (2009)Cite this article

For nucleosome-encoded epigenetic information to be transmitted, an epigenetic mark requires a 'reader' for its physical recognition. CENP-N has now been identified as a reader of the centromere-specifying epigenetic mark that is generated by incorporation of the histone H3 variant CENP-A into centromeric nucleosomes.

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Figure 1: Physical features that could be recognized by a reader of centromere-specifying nucleosomes.
Figure 2: Distinct modes of epigenetic propagation at the pericentromere and centromere.

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Authors and Affiliations

  1. Nikolina Sekulic and Ben E. Black are in the Department of Biochemistry and Biophysics, University of Pennsylvania, PA 19104–6059, USA. blackbe@mail.med.upenn.edu,

    Nikolina Sekulic & Ben E. Black

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  1. Nikolina Sekulic
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  2. Ben E. Black
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Sekulic, N., Black, B. A reader for centromeric chromatin. Nat Cell Biol 11, 793–795 (2009). https://doi.org/10.1038/ncb0709-793

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