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Hitting the sweet spot

A method for producing large carbohydrate microarrays allows high-throughput, sensitive detection of carbohydrate–antibody interactions.

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Figure 1: Glycan immobilization and epitope recognition on a microarray.

©Bob Crimi

References

  1. Varki, A. Glycobiology 3, 97–130 (1993).

    Article  CAS  Google Scholar 

  2. Wang, D. et al. Nat. Biotechnol. 20, 275–281 (2002).

    Article  CAS  Google Scholar 

  3. Bertozzi, C.R. & Kiessling, L.L. Science 291, 2357–2364 (2001).

    Article  CAS  Google Scholar 

  4. Schwikowski, B., Uetz, P., & Fields, S. Nat. Biotechnol. 18, 1257–1261 (2000).

    Article  CAS  Google Scholar 

  5. Schulze, A. & Downward, J. Nat. Cell Biol. 3, E190–E195 (2001).

    Article  CAS  Google Scholar 

  6. Zhu, H. & Snyder, M. Curr. Opin. Chem. Biol. 5, 40–45 (2001).

    Article  CAS  Google Scholar 

  7. Leteux, C. et al. Glycobiology 8, 227–236 (1998).

    Article  CAS  Google Scholar 

  8. Houseman, B.T. & Mrksich, M. Topics Current Chem. 218, 1–44 (2002)

    Article  CAS  Google Scholar 

  9. Sears, P. & Wong, C.H. Science 291, 2344–2350 (2001).

    Article  CAS  Google Scholar 

  10. Gygi, S.P. & Aebersold, R. Curr. Opin. Chem. Biol. 4, 489–494 (2000).

    Article  CAS  Google Scholar 

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Kiessling, L., Cairo, C. Hitting the sweet spot. Nat Biotechnol 20, 234–235 (2002). https://doi.org/10.1038/nbt0302-234

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