Genetic circuits that process and permanently store information are created with recombinases that flip the orientation of DNA cassettes.
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Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase
Scientific Reports Open Access 01 April 2016
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References
Adleman, L.M. et al. J. Comput. Biol. 6, 53–63 (1999).
Purnick, P.E. & Weiss, R. Nat. Rev. Mol. Cell Biol. 10, 410–422 (2009).
Siuti, P. et al. Nat. Biotechnol. 31, 448–452 (2013).
Weber, W. & Fusseneger, M. Chem. Biol. 16, 287–297 (2009).
Yamamoto, S. & Kutsukake, K. J. Bacteriol. 188, 958–967 (2006).
Bonnet, J. et al. Science doi:10.1126/science.1232758 (28 March 2013).
Friedland, A.E. et al. Science 324, 1199–1202 (2009).
Livet, J. et al. Nature 450, 56–62 (2007).
Gardner, T.S. et al. Nature 403, 339–342 (2000).
Barrangou, R. et al. Science 315, 1709–1712 (2007).
Qi, L.S. et al. Cell 152, 1173–1183 (2013).
Zanton, S. & Pugh, B.F. Genes Dev. 20, 2250–2265 (2006).
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Maranhao, A., Ellington, A. Endowing cells with logic and memory. Nat Biotechnol 31, 413–415 (2013). https://doi.org/10.1038/nbt.2573
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DOI: https://doi.org/10.1038/nbt.2573
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Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase
Scientific Reports (2016)