A new method for amplifying DNA allows more-uniform sequencing coverage of the genome of a single cell.
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References
Wang, J., Fan, H.C., Behr, B. & Quake, S.R. Cell 150, 402–412 (2012).
Caldas, C. Nat. Biotechnol. 30, 408–410 (2012).
Evrony, G.D. Cell 151, 483–496 (2012)
Zong, C., Lu, S., Chapman, A.R. & Xie, X.S. Science 338, 1622–1626 (2012).
Dean, F.B., Nelson, J.R., Giesler, T.L. & Lasken, R.S. Genome Res. 11, 1095–1099 (2001).
Dean, F.B. et al. Proc. Natl. Acad. Sci. USA 99, 5261–5266 (2002).
Lasken, R.S. Nat. Rev. Microbiol. 10, 631–640 (2012).
Gundry, M., Li, W., Maqbool, S.B. & Vijg, J. Nucleic Acids Res. 40, 2032–2040 (2012).
Hou, Y. et al. Cell 148, 873–885 (2012).
Lasken, R.S. & Stockwell, T. BMC Biotechnol. 7, 19 (2007).
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Lasken, R. Single-cell sequencing in its prime. Nat Biotechnol 31, 211–212 (2013). https://doi.org/10.1038/nbt.2523
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DOI: https://doi.org/10.1038/nbt.2523
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