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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Congenital central hypoventilation syndrome (Ondine's curse): prenatal diagnosis and fetal breathing characteristics

Journal of Perinatology volume 29, pages 712–713 (2009)Cite this article

Abstract

We report a case of Congenital Central Hypoventilation syndrome (CCHS), diagnosed in utero at 18 weeks’ gestation analysis of repeats in the PHOX2b gene in fetal amniocytes and confirmed at delivery. Prenatal diagnosis allowed for serial detailed assessment of fetal breathing characteristics. Fetal breathing in this affected fetus was indistinguishable from breathing characteristics in the non-affected fetus.

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Authors and Affiliations

  1. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, New York Medical College/Westchester Medical Center, Valhalla, NY, USA

    G P Rajendran, M S Kessler & F A Manning

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  1. G P Rajendran
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  2. M S Kessler
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  3. F A Manning
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Correspondence to F A Manning.

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Rajendran, G., Kessler, M. & Manning, F. Congenital central hypoventilation syndrome (Ondine's curse): prenatal diagnosis and fetal breathing characteristics. J Perinatol 29, 712–713 (2009). https://doi.org/10.1038/jp.2009.59

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  • DOI: https://doi.org/10.1038/jp.2009.59

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