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Decrease in serum potassium levels post saline suppression test in primary aldosteronism: an under-recognised phenomenon?

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References

  1. Ahmed AH, Cowley D, Wolley M, Gordon RD, Xu S, Taylor PJ et al. Seated saline suppression testing for the diagnosis of primary aldosteronism: a preliminary study. J Clin Endocrinol Metab 2014; 99 (8): 2745–2753.

    Article  CAS  Google Scholar 

  2. Mulatero P, Milan A, Fallo F, Regolisti G, Pizzolo F, Fardella C et al. Comparison of confirmatory tests for the diagnosis of primary aldosteronism. J Clin Endocrinol Metab 2006; 91 (7): 2618–2623.

    Article  CAS  Google Scholar 

  3. Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M et al. Case detection, diagnosis, and treatment of subjects with primary aldosteronism: an endocrine society clinical practice. J Clin Endocrinol Metab 2008; 93 (9): 3266–3281.

    Article  CAS  Google Scholar 

  4. Espiner EA, Tucci JR, Jagger PI, Lauler DP . Effect of saline infusions on aldosterone secretion and electrolyte excretion in normal subjects and patients with primary aldosteronism. N Engl J Med 1967; 277 (1): 1–7.

    Article  CAS  Google Scholar 

  5. Kem DC, Weinberger MH, Mayes DM, Nugent CA . Saline suppression of plasma aldosterone in hypertension. Arch Intern Med 1971; 128 (3): 380–386.

    Article  CAS  Google Scholar 

  6. Stokes GS, Monaghan JC, Mennie BA . Use of an intravenous sodium load in screening for primary hyperaldosteronism. Aust N Z J Med 1984; 14 (3): 201–207.

    Article  CAS  Google Scholar 

  7. Kaplan NM . The current epidemic of primary aldosteronism: causes and consequences. J Hypertens 2004; 22 (5): 863–869.

    Article  CAS  Google Scholar 

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Correspondence to M H Lee.

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Lee, M., Moxey, J., Derbyshire, M. et al. Decrease in serum potassium levels post saline suppression test in primary aldosteronism: an under-recognised phenomenon?. J Hum Hypertens 30, 664–665 (2016). https://doi.org/10.1038/jhh.2016.7

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