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Comparability and reproducibility of the carotid-femoral pulse wave velocity measurements using a multi-element carotid tonometry sensor

Abstract

To evaluate the comparability and reproducibility of the carotid-femoral pulse wave velocity (PWV) measured by the newly developed device compared to that measured by the standard device and the validity of brachial-ankle PWV as a substitute of carotid-femoral PWV. We measured aortic PWV twice in 21 normotensive males by using the standard devices and the newly developed device. We also measured brachial-ankle PWV in the same subjects. There was a strong, significant correlation between aortic (carotid-femoral) PWV measured by using two different devices (r=0.741, P=0.00012). Inter-quartile range of the differences of carotid-femoral PWV measured by Form (0.75 m/s (−0.36, 0.39)) was smaller than that by Complior (1.67 m/s (−1.03, 0.63)). There was no correlation between carotid-femoral PWV, measured by either device, and brachial ankle PWV. Our present results suggest that carotid-femoral PWV measured by using Form was comparable to, and may be more reproducible than, that measured by Complior that has been widely used as a predictable marker for cardiovascular events. Our results also suggest brachial-ankle PWV may not be a substitute for carotid-femoral PWV.

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Acknowledgements

We thank Junko Yokouchi RN for her technical assistance. This work was supported in part by a grants-inaid from the Ministry of Education, Science and Culture, Japan (no. 16590439 and no. 19590541 for S Ueda).

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Ueda, I., Tagawa, T., Watanabe, S. et al. Comparability and reproducibility of the carotid-femoral pulse wave velocity measurements using a multi-element carotid tonometry sensor. J Hum Hypertens 22, 699–703 (2008). https://doi.org/10.1038/jhh.2008.57

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