Abstract
Three polyketides containing a pyrone ring, neofusapyrone, fusapyrone, and deoxyfusapyrone, were isolated from the marine-derived fungus Fusarium sp. FH-146. Their structures were determined by extensive 1D- and 2D-NMR and MS spectral analyses. Fusapyrone and deoxyfusapyrone were originally reported as α-pyrone derivatives; however, the revised structures indicate that they are γ-pyrone derivatives. These three compounds exhibited antimicrobial activities.
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Hiramatsu, F., Miyajima, T., Murayama, T. et al. Isolation and Structure Elucidation of Neofusapyrone from a Marine-derived Fusarium species, and Structural Revision of Fusapyrone and Deoxyfusapyrone. J Antibiot 59, 704–709 (2006). https://doi.org/10.1038/ja.2006.94
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DOI: https://doi.org/10.1038/ja.2006.94
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