Sir,
We report a case of cystoid macular oedema (CMO) after selective laser trabeculoplasty (SLT). An 89-year-old Caucasian woman with a previous complicated left cataract surgery was referred to our practice. Visual acuity was 6/12 in the right eye and 6/36 in the left eye. There was right cataract, a left posterior chamber intraocular lens with an absent posterior capsule, and left CMO (later confirmed on optical coherence tomography (OCT)).
She underwent right cataract surgery, while the left eye was treated with topical dexamethasone 0.1% q.i.d. and ketorolac q.i.d. Over 2 years, acuity in the left eye improved to 6/9; however, intraocular pressure (IOP) increased to 30 mm Hg. The topical steroid was ceased and topical brinzolamide (0.1% b.i.d.) commenced. On account of persisting elevated IOP and questionable compliance with brinzolamide, SLT was offered. Pre-laser acuity was 6/9 and IOP was 20 mm Hg on brinzolamide. A 180-degree inferior treatment was performed with 57 applications of 0.7 mJ and total energy of 40 mJ. There was no post-treatment uveitis.
The patient noticed decreasing vision and at 4 weeks acuity was reduced to 6/18. The IOP had improved to 10 mm Hg. Clinically, there was CMO, confirmed on OCT. Ketorolac drops q.i.d. were commenced and brinzolamide continued. Three weeks later acuity had improved to 6/6 with marked resolution of the macula both clinically and on OCT. The IOP remained at 12 mm Hg.
To our knowledge, this is the first reported case of CMO after SLT, which is considered a relatively safe and innocuous procedure.1, 2, 3 As inflammatory processes may be inherent to its mechanism of action,3 we postulate that upregulation of inflammatory pathways could have triggered a recurrence of the CMO, especially with an absent posterior capsule, allowing greater access of inflammatory mediators to the posterior segment. Other inflammatory reactions to SLT are well recognised, such as ciliary injection and anterior chamber inflammation,1, 2 and there is one report of choroidal effusion associated with severe inflammation.4
We recommend caution in using SLT in eyes with a tendency for developing CMO, especially if CMO has been prolonged or was associated with complicated cataract surgery. If SLT is required in such cases, one might consider pre-treating with a non-steroidal anti-inflammatory agent.
References
Realini T . Selective laser trabeculoplasty: a review. J Glaucoma 2008; 17 (6): 497–502.
Barkana M, Belkin Y . Selective laser trabeculoplasty. Surv Ophthalmol 2007; 52 (6): 634–654.
Stein P, Challa JD . Mechanisms of action and efficacy of argon laser trabeculoplasty and selective laser trabeculoplasty. Curr Opin Ophthalmol 2007; 18: 140–145.
Kim DY, Singh A . Severe iritis and choroidal effusion following selective laser trabeculoplasty. Ophthalmic Surg Lasers Imaging 2008; 39 (5): 409–411.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no conflict of interest.
Rights and permissions
About this article
Cite this article
Wechsler, D., Wechsler, I. Cystoid macular oedema after selective laser trabeculoplasty. Eye 24, 1113 (2010). https://doi.org/10.1038/eye.2009.249
Published:
Issue Date:
DOI: https://doi.org/10.1038/eye.2009.249
This article is cited by
-
Selective laser trabeculoplasty is safe and effective in patients previously treated with prostaglandin analogs: An evidence-based review
International Ophthalmology (2022)
-
„Laser trials“
Der Ophthalmologe (2021)
-
Cystoid macular edema following selective laser trabeculoplasty in a patient with ocular hypertension
International Ophthalmology (2019)
-
Where does selective laser trabeculoplasty stand now? A review
Eye and Vision (2016)