Abstract
Recent studies of neurotrophin knockout mice shed light on the distinct requirements for neurotrophins in the central as compared to the peripheral nervous system. These findings reveal pleiotropic roles for neurotrophins including roles in neuronal patterning and differentiation.
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Schwartz, P., Levy, R., Borghesani, P. et al. Cerebellar pathology in BDNF −/− mice: the classic view of neurotrophins is changing. Mol Psychiatry 3, 116–118 (1998). https://doi.org/10.1038/sj.mp.4000359
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DOI: https://doi.org/10.1038/sj.mp.4000359