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Old and new models for the study of human ageing

Nature Reviews Molecular Cell Biology volume 21, pages 491–493 (2020)Cite this article

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Human ageing is associated with high susceptibility to disease. Some aspects of ageing can be studied directly in humans and have revealed that ageing is influenced by many factors, including genetics, lifestyle, sex and socio-economic status. But identifying the factors that cause and modulate the ageing process often requires experimental interventions and modelling that can only be performed in model systems.

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Acknowledgements

A.B. would like to thank C. Bedbrook, R. Nath and L. Xu for helpful suggestions and gratefully acknowledges a generous philanthropic gift from M. and T. Barakett.

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Authors and Affiliations

  1. Department of Genetics, Stanford University, Stanford, CA, USA

    Anne Brunet

  2. Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, CA, USA

    Anne Brunet

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  1. Anne Brunet
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Correspondence to Anne Brunet.

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Brunet, A. Old and new models for the study of human ageing. Nat Rev Mol Cell Biol 21, 491–493 (2020). https://doi.org/10.1038/s41580-020-0266-4

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