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Hematology

Relapsed and refractory PTCL—into the therapeutic abyss

Outcomes in patients with peripheral T-cell lymphomas are poor and there are no established standards of care for patients in the relapsed and refractory setting, owing in part to the lack of multicenter, controlled clinical trials. Recently, encouraging results were reported in this setting with pralatrexate—a novel folate analog.

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F. Foss is a consultant for and receives honoraria from Allos, Celgene and Eisai. She is a consultant for and receives research support from Merck and she receives honoraria from Cephalon.

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Foss, F. Relapsed and refractory PTCL—into the therapeutic abyss. Nat Rev Clin Oncol 8, 321–322 (2011). https://doi.org/10.1038/nrclinonc.2011.51

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