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Ubiquitin regulation of neuronal excitability

Nature Neuroscience volume 14, pages 126–128 (2011)Cite this article

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Demonstrating the common mechanism of proteasome-dependent degradation of ion channels, two studies in this issue of Nature Neuroscience show that ubiquitin-dependent protein degradation can modulate neuronal excitability.

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Figure 1: Ubiquitin controls neuronal excitability and synaptic transmission by regulating ion channel stability and trafficking.

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Authors and Affiliations

  1. Sriharsha Kantamneni, Kevin A. Wilkinson and Jeremy M. Henley are at the Medical Research Council Centre for Synaptic Plasticity, School of Biochemistry, Medical Sciences Building, University of Bristol, Bristol, UK.,

    Sriharsha Kantamneni, Kevin A Wilkinson & Jeremy M Henley

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  1. Sriharsha Kantamneni
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  2. Kevin A Wilkinson
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  3. Jeremy M Henley
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Correspondence to Jeremy M Henley.

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Kantamneni, S., Wilkinson, K. & Henley, J. Ubiquitin regulation of neuronal excitability. Nat Neurosci 14, 126–128 (2011). https://doi.org/10.1038/nn0211-126

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