Abstract
CURRENT interest in the structure of cell plasma membranes arises partly from demonstrations that specific receptors for hormones (for example, insulin and glucagon1), drugs and other biologically active molecules (for example, Phaseolus vulgaris phytohaemagglutinin2, concanavalin A3 and acetylcholine4,5) are frequently located at the cell surface. Isolation of these receptors has, however, been impeded by the insolubility of cell membranes in the more orthodox biochemical solvents, whereas more drastic solubilization procedures have usually destroyed biological activity6.
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ALLAN, D., AUGER, J. & CRUMPTON, M. Glycoprotein Receptors for Concanavalin A isolated from Pig Lymphocyte Plasma Membrane by Affinity Chromatography in Sodium Deoxycholate. Nature New Biology 236, 23–25 (1972). https://doi.org/10.1038/newbio236023a0
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DOI: https://doi.org/10.1038/newbio236023a0
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