A small-molecule inhibitor of protein secretion has been found that targets Cdc42, a regulator of the secretory pathway. This compound acts through a previously undescribed mechanism—by recruiting a protein inhibitor.
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Stockwell, B. Preventing protein secretion with chemical glue. Nat Chem Biol 2, 7–8 (2006). https://doi.org/10.1038/nchembio0106-7
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DOI: https://doi.org/10.1038/nchembio0106-7
