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It takes three to tango

Nature Biotechnology volume 20, pages 1210–1212 (2002)Cite this article

The recently determined high-resolution crystal structure of the bacterial multidrug resistance transporter AcrB brings us one step closer to the design of more effective therapeutic agents.

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Figure 1: Structural studies of the multidrug resistance RND transporter AcrB of E. coli reveal a trimeric protein.

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Author information

Authors and Affiliations

  1. associate director of Efflux Biology at Essential Therapeutics, Inc., Mountain View, 94043, CA

    Olga Lomovskaya

  2. assistant professor in the Department of Chemistry & Biochemistry at the University of Oklahoma, Norman, 73019-3051, OK

    Helen I. Zgurskaya

  3. professor in the Department of Molecular & Cell Biology at the University of California, Berkeley, Berkeley, 94720-3206, CA

    Hiroshi Nikaido

Authors
  1. Olga Lomovskaya
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  2. Helen I. Zgurskaya
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  3. Hiroshi Nikaido
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Lomovskaya, O., Zgurskaya, H. & Nikaido, H. It takes three to tango. Nat Biotechnol 20, 1210–1212 (2002). https://doi.org/10.1038/nbt1202-1210

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