Abstract
Multiply marked X, 2nd and 3rd chromosomes were used to study the patterns of regional specificity of effects on crossing over of chromosomes from a stock of D. melanogaster selected for high Gl-Sb recombination. It was found that the HX chromosome increased crossover frequencies more or less uniformly throughout chromosome 3, and did not significantly affect coincidence coefficients. The H 3rd chromosome increased crossing over most strongly in the proximal region of chromosome 3, and in the distal region of the X chromosome, although effects could be detected on other parts of the X and 3rd chromosomes. 2nd chromosome recombination was, however, reduced by the H 3rd chromosome. Coincidence coefficients were increased in chromosome 3 by the H 3rd chromosome, but no significant effects on the X or 2nd chromosomes could be detected.
The H genome significantly reduced the frequency of X chromosome non-disjunction, but had no detectable effect on chromosome 3 non-disjunction. Heterozygosity for a 2nd chromosome balancer (SM1) increased 3rd chromosome non-disjunction, but had no effect on the X.
These findings are discussed in relation to other genetic studies of Drosophila recombination, and to the problem of the evolutionary modification of recombination rates.
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Charlesworth, B., Mori, I. & Charlesworth, D. Genetic variation in recombination in Drosophila. III. Regional effects on crossing over and effects on non-disjunction. Heredity 55, 209–221 (1985). https://doi.org/10.1038/hdy.1985.93
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DOI: https://doi.org/10.1038/hdy.1985.93