γδ T cells are the misunderstood siblings of the antigen receptor family. A recent paper in Nature that describes the crystal structure of a γδ TCR should initiate a clearer understanding of these enigmatic cells.
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References
Garcia, K. C., Teyton, L. & Wilson, I. A. Annu. Rev. Immunol. 17 369–397 (1999).
Allison, T. J., Winter, C. C., Fournié, J. -J., Bonneville, M. & Garboczi, D. N. Nature 411, 820–824 (2001).
Hayday, A. C. Annu. Rev. Immunol. 18, 975–1026 (2000).
Parker, C. M. et al. J. Exp. Med. 171, 1597–1612 (1990).
Morita, C. T. et al. Immunity 3, 495–507 (1995).
Belmant, C. et al. J. Biol. Chem. 274, 32079–32084 (1999).
Chien, Y.-H., Jores, R. & Crowley, M. P. Annu. Rev. Immunol. 14, 511–532 (1996).
Moody, D. B., Besra, G., Wilson, I. A. & Porcelli, S. A. Immunol. Rev. 172, 285–296 (1999).
Li, H. et al. Nature 391, 502–506 (1998).
Wilson, I. A. & Stanfield, R. L. Curr. Opin. Struct. Biol. 3, 113–118 (1993).
Johnson, G. & Wu, T. T. Nucleic Acids Res. 29, 205–206 (2001).
Berman, H. M. et al. Nucleic Acids Res. 28, 235–242 (2000).
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We thank the Garboczi lab for providing the coordinates before publication.
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Wilson, I., Stanfield, R. Unraveling the mysteries of γδ T cell recognition. Nat Immunol 2, 579–581 (2001). https://doi.org/10.1038/89718
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DOI: https://doi.org/10.1038/89718
