A network of Hox factors specifies the identity of motor neurons in the spinal cord. Studies of an essential Fox-class accessory factor illuminate the developmental and evolutionary subtlety of the process.
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References
Jessell, T. M. Nature Rev. Genet. 1, 20–29 (2000).
Dasen, J. S., Tice, B. C., Brenner-Morton, S. & Jessell, T. M. Cell 123, 477–491 (2005).
Dasen, J. S., De Camilli, A., Wang, B., Tucker, P. W. & Jessell, T. M. Cell 134, 304–316 (2008).
Rousso, D. L., Gaber, Z. B., Wellik, D., Morrisey, E. E. & Novitch, B. G. Neuron 59, 226–240 (2008).
Shirasaki, R. & Pfaff, S. L. Annu. Rev. Neurosci. 25, 251–281 (2002).
Mann, R. S. & Affolter, M. Curr. Opin. Genet. Dev. 8, 423–429 (1998).
Moens, C. B. & Selleri, L. Dev. Biol. 291, 193–206 (2006).
Fetcho, J. R. Brain Behav. Evol. 40, 82–97 (1992).
True, J. R. & Carroll, S. B. Annu. Rev. Cell Dev. Biol. 18, 53–80 (2002).
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Pfaff, S. Hox and Fox. Nature 455, 295–297 (2008). https://doi.org/10.1038/455295a
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DOI: https://doi.org/10.1038/455295a
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