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Cell biology

Aneuploidy and cancer

Aneuploidy is the condition in which a cell has extra or missing chromosomes, and is often associated with tumours. But whether it is a cause or a consequence of cancer remains a vexed question.

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Figure 1: Different routes to aneuploidy.

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Pellman, D. Aneuploidy and cancer. Nature 446, 38–39 (2007). https://doi.org/10.1038/446038a

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