Channels that conduct anions or cations across cell membranes are of immense physiological importance. But what do they look like? A chloride channel turns out to have a double-barrelled structure quite unlike that of cation channels.
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References
Hille, B. Ionic Channels of Excitable Membranes (Sinauer, Sunderland, MA, 1992).
MacKinnon, R. Neuron 14, 889–892 (1995).
Middleton, R. E., Pheasant, D. J. & Miller, C. Nature 383, 337–340 (1996).
Ludewig, U., Pusch, M. & Jentsch, T. J. Nature 383, 340–343 (1996).
Miller, C. & Richard, E. A. in Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells (eds Alvarez-Leefmans, F. J. & Russell, J. M.) 383–405 (Plenum, New York, 1990).
Middleton, R. E., Pheasant, D. J. & Miller, C. Biochemistry 33, 13189–13198 (1994).
Steinmeyer, K., Lorenz, C., Pusch, M., Koch, M. C. & Jentsch, T. J. EMBO J. 13, 737–743 (1994).
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Gadsby, D. Two-bit anion channel really shapes up. Nature 383, 295–296 (1996). https://doi.org/10.1038/383295a0
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DOI: https://doi.org/10.1038/383295a0
