As the oldest, naturally occurring, treatment for malaria, quinine has been a target for synthetic chemistry for 150 years. At last, modern techniques provide full control over the synthetic molecule.
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Weinreb, S. Synthetic lessons from quinine. Nature 411, 429–431 (2001). https://doi.org/10.1038/35078178
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DOI: https://doi.org/10.1038/35078178
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