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Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter

Nature volume 319, pages 640–646 (1986)Cite this article

Abstract

Complementary DNA encoding the IgG1 induction factor, the first lymphokine directed to B lymphocytes, from a murine T-cell line has been cloned using a new strategy. The putative primary amino-acid sequence was deduced from the nucleotide sequence determined. The lymphokine synthesized by the direction of this cloned cDNA has many other functions, such as production of B-cell growth factor-1 and induction of Ia on B cells.

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References

  1. Honjo, T. & Kataoka, T. Proc. natn. Acad. Sci U.S.A. 75, 2140–2144 (1978).

    Article  CAS  ADS  Google Scholar 

  2. Kataoka, T., Kawakami, T., Takahashi, N. & Honjo, T. Proc. natn. Acad. U.S.A. 77, 919–923 (1980).

    Article  CAS  ADS  Google Scholar 

  3. Davis, M. M. et al. Nature 283, 733–739 (1980).

    Article  CAS  ADS  PubMed  Google Scholar 

  4. Sakano, H., Maki, R., Kurosawa, Y., Roeder, W. & Tonegawa, S. Nature 286, 676–683 (1980).

    Article  CAS  ADS  PubMed  Google Scholar 

  5. Kataoka, T., Miyata, T. & Honjo, T. Cell 23, 357–368 (1981).

    Article  CAS  PubMed  Google Scholar 

  6. Yaoita, Y. & Honjo, T. Nature 286, 850–853 (1980).

    Article  CAS  ADS  PubMed  Google Scholar 

  7. Nikaido, T., Yamawaki-Kataoka, Y. & Honjo, T. J. biol. Chem. 257, 7322–7329 (1982).

    CAS  PubMed  Google Scholar 

  8. Perlmutter, R. M., Hansburg, D., Briles, D., Nicolotti, R. A. & Davie, J. M. J. Immun. 121, 566–572 (1978).

    CAS  PubMed  Google Scholar 

  9. Slack, J. N., Der-Balian, G. P., Nahm, M. & Davie, J. M. J. exp. Med. 151, 853–862 (1980).

    Article  CAS  PubMed  Google Scholar 

  10. Izui, S., Eisenberg, R. A. & Dixon, F. J. J. exp. Med. 153, 324–338 (1981).

    Article  CAS  PubMed  Google Scholar 

  11. Cebra, J. J., Komisar, J. I. & Schweitzer, P. A. A. Rev. Immun. 2, 493–548 (1984).

    Article  CAS  Google Scholar 

  12. Isakson, P. C., Pure, E., Vitteta, E. S. & Krammer, P. H. J. exp. Med. 155, 734–748 (1982).

    Article  CAS  PubMed  Google Scholar 

  13. Coutinho, A., Pettersson, S., Ruuth, E. & Forni, L. Eur. J. Immun. 13, 269–272 (1983).

    Article  CAS  Google Scholar 

  14. Bergstedt-Lindquist, S., Sideras, P., MacDonald, H. R. & Severinson, E. Immun. Rev. 78, 25–50 (1984).

    Article  Google Scholar 

  15. Kishimoto, T. A. Rev. Immun. 3, 133–158 (1985).

    Article  CAS  Google Scholar 

  16. Okayama, H. & Berg, P. Molec. cell. Biol. 3, 280–289 (1983).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Yokota, T. et al. Proc. natn. Acad. Sci. U.S.A. 81, 1070–1074 (1984).

    Article  CAS  ADS  Google Scholar 

  18. Melton, D. A. et al. Nucleic Acids Res. 12, 7035–7056 (1984).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Krieg, P. A. & Melton, D. A. Nucleic Acids Res. 12, 7057–7070 (1984).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Sideras, P., Bergstedt-Lindquist, S., MacDonald, H. R. & Severinson, E. Eur. J. Immun. 15, 586–593 (1985).

    Article  CAS  Google Scholar 

  21. Gurdon, J. B., Lane, C. D. & Woodland, H. R. Nature 233, 177–184 (1971).

    Article  CAS  ADS  PubMed  Google Scholar 

  22. Yokota, T. et al. Proc. natn. Acad. Sci. U.S.A. 82, 68–72 (1985).

    Article  CAS  ADS  Google Scholar 

  23. Sanger, F., Nicklen, S. & Coulson, A. R. Proc. natn. Acad. Sci. U.S.A. 74, 5463–5469 (1977).

    Article  CAS  ADS  Google Scholar 

  24. Altenburger, W., Steinmetz, M. & Zachau, H. G. Nature 287, 603–607 (1980).

    Article  CAS  ADS  PubMed  Google Scholar 

  25. Kim, S., Davis, M., Sinn, E., Patten, P. & Hood, L. Cell 27, 573–581 (1981).

    Article  CAS  PubMed  Google Scholar 

  26. Rechavi et al. Proc. natn. Acad. Sci. U.S.A. 79, 4405–4409 (1982).

    Article  CAS  ADS  Google Scholar 

  27. Howard, M. & Paul, W. E. A. Rev. Immunol. 1, 307–333 (1983).

    Article  CAS  Google Scholar 

  28. Sideras, P., Bergstedt-Lindqvist, S. & Severinson, E. Eur. J. Immun. 15, 593–598 (1985).

    Article  CAS  Google Scholar 

  29. Noelle, R., Krammer, P. H., Ohara, J., Uhr, J. W. & Vitetta, E. S. Proc. natn. Acad. Sci. U.S.A. 81, 6149–6153 (1984).

    Article  CAS  ADS  Google Scholar 

  30. Möller, G. (ed.) Immun. Rev. 78 (1984).

  31. Schimpl, A. & Wecker, E. Transplantn Rev. 23, 176–188 (1975).

    CAS  Google Scholar 

  32. Swain, S. & Dutton, R. J. exp. Med. 156, 1821–1834 (1982).

    Article  CAS  PubMed  Google Scholar 

  33. Howard, M. et al. J. exp. Med. 155, 914–923 (1982).

    Article  CAS  PubMed  Google Scholar 

  34. Anderson, J. & Melchers, F. Proc. natn. Acad. Sci. U.S.A. 78, 2497–2501 (1981).

    Article  CAS  ADS  Google Scholar 

  35. Leanderson, T. et al. Proc. natn. Acad. Sci. U.S.A. 79, 7455–7459 (1982).

    Article  CAS  ADS  Google Scholar 

  36. Aarden, L. A. et al. J. Immun. 123, 2928–2929 (1979).

    CAS  Google Scholar 

  37. Ullrich, A. et al. Science 196, 1313–1319 (1977).

    Article  CAS  ADS  PubMed  Google Scholar 

  38. Konarska, M. M., Padgett, R. A. & Sharp, P. A. Cell 38, 731–736 (1984).

    Article  CAS  PubMed  Google Scholar 

  39. Makmaster, G. K. & Carmichael, G. G. Proc. natn. Acad. Sci. U.S.A. 74, 4835–4838 (1977).

    Article  ADS  Google Scholar 

  40. Gronowicz, E., Couthino, A. & Melchers, F. Eur. J. Immun. 6, 588–590 (1976).

    Article  CAS  Google Scholar 

  41. Gough, N. M., Metcalf, D., Gough, J., Grail, D. & Dunn, A. R. EMBO J. 4, 645–653 (1985).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  42. Gray, P. W. & Goeddel, D. V. Proc. natn. Acad. Sci. U.S.A. 80, 5842–5846 (1983).

    Article  CAS  ADS  Google Scholar 

  43. Lemke, H., Hammerling, G. J. & Hammerling, U. Immun. Rev. 47, 175–206 (1979).

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Medical Chemistry, Faculty of Medicine, Kyoto University, Kyoto, 606, Japan

    Yoshihiko Noma, Takayuki Naito, Chihiro Azuma, Toshizumi Tanabe, Tatsuo Kinashi, Fumihiko Matsuda, Yoshio Yaoita & Tasuku Honjo

  2. Department of Immunobiology, Karolinska Institute, Wallenberg Laboratory, Lilla Frescati, S-104 05, Stockholm, 50, Sweden

    Paschalis Sideras, Susanne Bergstedt-Lindquist & Eva Severinson

Authors
  1. Yoshihiko Noma
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  2. Paschalis Sideras
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  4. Susanne Bergstedt-Lindquist
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  5. Chihiro Azuma
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  6. Eva Severinson
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  7. Toshizumi Tanabe
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  10. Yoshio Yaoita
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  11. Tasuku Honjo
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Noma, Y., Sideras, P., Naito, T. et al. Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter. Nature 319, 640–646 (1986). https://doi.org/10.1038/319640a0

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