Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Sea urchin histone mRNA termini are located in gene regions downstream from putative regulatory sequences

Abstract

S1 nuclease mapping of the Psammechinus miliaris embryonic histone mRNAs locates the 5′ termini in or adjacent to a short sequence homology (5′ pyCATTCpu3′) downstream from the putative RNA polymerase II regulatory sequence (5′TATAAATA3′) or related sequences. The 3′ termini map just after a sequence containing GC-rich hyphenated dyad symmetry, a feature of most known terminator sequences.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Birnstiel, M. L. & Chipchase, M. Trends biochem. Sci. 2, 149–152 (1977).

    Article  CAS  Google Scholar 

  2. Hentschel, C. C. & Birnstiel, M. L. in Proc. FEBS Symp. DNA, Prague (eds Zadrazil, S. & Sponar, J.) (Pergamon, Oxford, 1980).

    Google Scholar 

  3. Probst, E., Kressmann, A. & Birnstiel, M. L. J. molec. Biol. 135, 709–732 (1979).

    Article  CAS  Google Scholar 

  4. Grosschedl, R. & Birnstiel, M. L. Proc. natn. Acad. Sci. U.S.A. 77, 1432–1436 (1980).

    Article  ADS  CAS  Google Scholar 

  5. Clarkson, S. G., Smith, H. O., Schaffner, W., Gross, K. W. & Birnstiel, M. L. Nucleic Acids Res. 3, 2617–2632 (1976).

    Article  CAS  Google Scholar 

  6. Schaffner, W. et al. Cell 14, 655–671 (1978).

    Article  CAS  Google Scholar 

  7. Kedes, L. H. A. Rev. Biochem. 48, 837–870 (1979).

    Article  CAS  Google Scholar 

  8. Busslinger, M., Portmann, R., Irminger, J. C. & Birnstiel, M. L. Nucleic Acids Res. 8, 957–977 (1980).

    Article  CAS  Google Scholar 

  9. Busslinger, M., Portmann, R. & Birnstiel, M. L. Nucleic Acids Res. 9, 2997–3008 (1979).

    Article  Google Scholar 

  10. Gannon, F. et al. Nature 278, 428–434 (1979).

    Article  ADS  CAS  Google Scholar 

  11. Berk, A. J. & Sharp, P. A. Proc. natn. Acad. Sci. U.S.A. 75, 1274–1278 (1978).

    Article  ADS  CAS  Google Scholar 

  12. Tsujimoto, Y. & Suzuki, Y. Cell 16, 425–436 (1979).

    Article  CAS  Google Scholar 

  13. Moss, T. & Birnstiel, M. L. Nucleic Acids Res. 6, 3733–3743 (1979).

    Article  CAS  Google Scholar 

  14. Weaver, R. F. & Weissmann, C. Nucleic Acids Res. 7, 1175–1195 (1979).

    Article  CAS  Google Scholar 

  15. Maxam, A. M. & Gilbert, W. Proc. natn. Acad. Sci. U.S.A. 74, 560–564 (1974).

    Article  ADS  Google Scholar 

  16. Sanger, F. & Coulson, A. R. FEBS Lett. 87, 107–110 (1977).

    Google Scholar 

  17. McConnell, D. J., Searcy, D. G. & Sutcliffe, J. G. Nucleic Acids Res. 5, 1729–1739 (1978).

    Article  CAS  Google Scholar 

  18. Sollner-Webb, B. & Reeder, B. Cell 18, 485–499 (1979).

    Article  CAS  Google Scholar 

  19. Baker, C. C., Herisse, J., Courtois, G., Galibert, F. & Ziflf, E. Cell 18, 569–581 (1979).

    Article  CAS  Google Scholar 

  20. Surrey, S. & Nemer, M. Cell 9, 589–595 (1976).

    Article  CAS  Google Scholar 

  21. Faust, M., Millward, S., Duchastel, A. & Fromson, D. Cell 7, 597–604 (1976).

    Article  Google Scholar 

  22. Grunstein, M. & Grunstein, J. E. Cold Spring Harb. Symp. quant. Biol. 42, 1083–1092 (1977).

    Article  Google Scholar 

  23. Tsuda, M., Ohshima, Y. & Suzuki, Y. Proc. natn. Acad. Sci. U.S.A. 76, 4872–4876 (1979).

    Article  ADS  CAS  Google Scholar 

  24. Ziff, E. B. & Evans, R. M. Cell 15, 1463–1475 (1978).

    Article  CAS  Google Scholar 

  25. Rosenberg, M. & Court, D. A. Rev. Genet. 13, 319–353 (1979).

    Article  CAS  Google Scholar 

  26. Salditt-Georgieff, M., Harpold, M., Chen-Kiang, S. & Darnell, J. E. Cell 19, 69–78 (1980).

    Article  CAS  Google Scholar 

  27. Korn, L. & Brown, D. Cell 15, 1145–1156 (1978).

    Article  CAS  Google Scholar 

  28. Scherer, G. E. F., Walkinshaw, N. D. & Arnott, S. Nucleic Acids Res. 5, 3759–3773 (1978).

    Article  CAS  Google Scholar 

  29. Sutcliffe, J. G. Nucleic Acids Res. 5, 2721–2728 (1978).

    Article  CAS  Google Scholar 

  30. Levy, S., Sures, I. & Kedes, L. H. Nature 279, 737–739 (1979).

    Article  ADS  CAS  Google Scholar 

  31. Pribnow, D. in Biological Regulation and Development Vol. 1 (ed. Goldberger, R.F.) 250–277 (Plenum, New York, 1979).

    Google Scholar 

  32. Adhya, S. & Gottesman, M. A. Rev. Biochem. 47, 967–997 (1978).

    Article  CAS  Google Scholar 

  33. Vogt, V. M. Eur. J. Biochem. 33, 192–200 (1973).

    Article  CAS  Google Scholar 

  34. Laskey, R. A. & Mills, A. D. FEBS Lett. 82, 314–316 (1977).

    Article  CAS  Google Scholar 

  35. Maniatis, T., Jeffrey, A. & Kleid, D. G. Proc. natn. Acad. Sci. U.S.A. 72, 1184–1188 (1975).

    Article  ADS  CAS  Google Scholar 

  36. Gurmstbein, M. & Schedl, P. J. molec. Biol. 104, 325–349 (1976).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hentschel, C., Irminger, JC., Bucher, P. et al. Sea urchin histone mRNA termini are located in gene regions downstream from putative regulatory sequences. Nature 285, 147–151 (1980). https://doi.org/10.1038/285147a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/285147a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing