Abstract
THE transmission of Creutzfeldt–Jakob disease of man, one of the subacute spongiform virus encephalopathies1, to guinea pigs2,3 and to hamsters4 has been reported from this laboratory; Brownell et al. have also claimed transmission of Creutzfeldt–Jakob disease to mice5,6. Here we present evidence that mice are susceptible to this transmissible encephalopathy and that there are similarities between the clinical and pathological findings in experimental Creutzfeldt–Jakob disease in mice, and those observed in the same host in experimental scrapie7–11.
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MANUELIDIS, E., GORGACZ, E. & MANUELIDIS, L. Transmission of Creutzfeldt–Jakob disease with scrapie-like syndromes to mice. Nature 271, 778–779 (1978). https://doi.org/10.1038/271778a0
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DOI: https://doi.org/10.1038/271778a0
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