Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Repeating sequences in aminoacyl-tRNA synthetases

Abstract

Some aminoacyl-tRNA synthetases have elongated by fusing two very similar sequences.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Holley, R., Apgar, J., Everett, G., Madison, J., Marquisee, M., Merrill, S., Penswick, J., and Zamir, A., Science, 147, 1462 (1965).

    Article  ADS  CAS  Google Scholar 

  2. Arndt, D. J., and Berg, P., J. biol. Chem., 245, 665 (1970).

    CAS  PubMed  Google Scholar 

  3. Yarus, M., and Berg, P., J. molec. Biol., 28, 479 (1967).

    Article  CAS  Google Scholar 

  4. Blanquet, S., Fayat, G., Waller, J. P., and Iwatsubo, M., Eur. J. Biochem., 24, 461 (1972).

    Article  CAS  Google Scholar 

  5. Muench, K. R., and Joseph, D. R., Miami Winter Symposium, 2, 172 (1971).

    Google Scholar 

  6. Fasolo, F., Befort, N., Boulanger, Y., and Ebel, J. P., Biochim. biophys. Acta, 217, 305 (1970).

    Article  Google Scholar 

  7. Ostrem, D. L., and Berg, P., Proc. natn. Acad. Sci U.S.A., 67, 1967 (1970).

    Article  ADS  CAS  Google Scholar 

  8. Andrews, P., Biochem. J., 91, 222 (1964).

    Article  CAS  Google Scholar 

  9. Laemmli, U. K., Nature, 227, 680 (1970).

    Article  ADS  CAS  Google Scholar 

  10. Ullmann, A., Goldberg, M. E., Perrin, D., and Monod, J., Biochemistry, 7, 261 (1968).

    Article  CAS  Google Scholar 

  11. Hartley, R. W., and Barber, E. A., Nature new Biol., 235, 15 (1972).

    Article  CAS  Google Scholar 

  12. Schroeder, W. A., Methods in Enzymology, 25, 203 (1972).

    Google Scholar 

  13. Crestfield, A. M., Stein, W. H., and Moore, S., J. biol. Chem., 238, 2413 (1963).

    CAS  PubMed  Google Scholar 

  14. Edelman, G. M., Cunningham, B. A., Reeke, G. N., Becker, J. W., Waxdal, M. J., and Wang, J. L., Proc. natn. Acad. Sci. U.S.A., 69, 2580 (1972).

    Article  ADS  CAS  Google Scholar 

  15. Black, J. A., and Dixon, G. H., Nature, 218, 736 (1968).

    Article  ADS  CAS  Google Scholar 

  16. Coffee, C. J., Aaronson, R. P., and Frieden, C., J. biol. Chem., 248, 1381 (1973).

    CAS  PubMed  Google Scholar 

  17. Edelhoch, H., Biochemistry, 6, 1948 (1967).

    Article  CAS  Google Scholar 

  18. Edelhoch, H., J. biol. Chem., 243, 3557 (1968).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Koch, G., Boulanger, Y. & Hartley, B. Repeating sequences in aminoacyl-tRNA synthetases. Nature 249, 316–320 (1974). https://doi.org/10.1038/249316a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/249316a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing