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Strain Differences in Thymus Weight in Mice with Different Predispositions to Spontaneous Mammary Cancer

Nature volume 237, pages 401–402 (1972)Cite this article

Abstract

IT has been demonstrated that early thymectomy in high mammary tumour strains of mice results in retarded development of spontaneous mammary tumours1–7. We have shown that early thymectomy also inhibits the growth of syngeneic transplantable tumour in the high cancer C3H/He mouse strain8, whereas the transplantation of one to four additional syngeneic thymuses stimulates the growth of this tumour9. Thus, it appears that the thymus exerts an influence on mammary tumour development in high cancer strains of mice.

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References

  1. Martinez, C., Nature, 203, 1188 (1964).

    Article  ADS  CAS  Google Scholar 

  2. Law, L. W., Cancer Res., 26, 1, 551 (1966).

    Google Scholar 

  3. Heppner, G. H., Proc. Amer. Assoc. Cancer Res., 8, 2, 27 (1967).

    ADS  Google Scholar 

  4. Sakakura, T., and Nishizuka, Ya., Japan. J. Cancer Res., 58, 441 (1965).

    Google Scholar 

  5. Heppner, G. H., Wood, P. C., and Weiss, D. W., Israel J. Med. Sci., 4, 1195 (1968).

    CAS  PubMed  Google Scholar 

  6. Heppner, G. H., Wood, P. C., and Weiss, D. W., Israel J. Med. Sci., 4, 1204 (1968).

    CAS  PubMed  Google Scholar 

  7. Yunis, E. J., Martinez, C., Smith, J., Stutman, O., and Good, R. S., Cancer Res., 29, 174 (1969).

    CAS  PubMed  Google Scholar 

  8. Gruntenko, E. V., Videlez, I. Yu., and Belyaev, D. K., Proc. Acad. Sci. USSR, 186, 1217 (1969).

    CAS  Google Scholar 

  9. Belyaev, D. K., and Gruntenko, E. V., Genetica (USSR), 6, 1, 54 (1970).

    Google Scholar 

  10. Metcalf, D., Cancer Res., 26, 1347 (1960).

    Google Scholar 

  11. Lobanova, Z. I., and Blandova, Z. K., in Biology of Laboratory Animals, third ed. (edit. by Doushkin, V. A.) (Moscow, 1971).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Cytology and Genetics, Siberian Department, USSR Academy of Sciences, Novosibirsk

    D. K. BELYAEV & E. V. GRUNTENKO

Authors
  1. D. K. BELYAEV
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  2. E. V. GRUNTENKO
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BELYAEV, D., GRUNTENKO, E. Strain Differences in Thymus Weight in Mice with Different Predispositions to Spontaneous Mammary Cancer. Nature 237, 401–402 (1972). https://doi.org/10.1038/237401a0

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