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Epstein–Barr Virus in Burkitt's Lymphoma and Nasopharyngeal Carcinoma: Antibodies to EBV associated Membrane and Viral Capsid Antigens in Burkitt Lymphoma Patients

Nature volume 228, pages 1053–1056 (1970)Cite this article

Abstract

Serological tests on 96 Burkitt lymphoma patients reveal antibody activity against virus-determined membrane antigen and viral capsid antigen while nucleic acid hybridization results on Burkitt's lymphoma and nasopharyngeal carcinoma add confirmatory evidence of an intimate association between the viral genome and the two diseases.

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Authors and Affiliations

  1. Institute for Tumour Biology, Karolinska Institutet, 104 01 Stockholm 60, Sweden

    PETER GUNVÉN & GEORGE KLEIN

  2. Virus Laboratories, The Children's Hospital of Philadelphia, Philadelphia, 19146, Pennsylvania

    GERTRUDE HENLE & WERNER HENLE

  3. Department of Head and Neck Surgery, Kenyatta National Hospital, PO Box 30024, Nairobi

    PETER CLIFFORD

Authors
  1. PETER GUNVÉN
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  2. GEORGE KLEIN
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  3. GERTRUDE HENLE
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  4. WERNER HENLE
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  5. PETER CLIFFORD
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GUNVÉN, P., KLEIN, G., HENLE, G. et al. Epstein–Barr Virus in Burkitt's Lymphoma and Nasopharyngeal Carcinoma: Antibodies to EBV associated Membrane and Viral Capsid Antigens in Burkitt Lymphoma Patients. Nature 228, 1053–1056 (1970). https://doi.org/10.1038/2281053a0

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