Abstract
WE have found evidence of high activity of the enzyme glutamate decarboxylase (GAD) outside the nervous system. This enzyme catalyses the formation of γ-amino-butyric acid (GABA), which is believed to be an inhibitory neurotransmitter1. Recently, however, a high concentration of GABA (11 mmoles/kg wet weight) was found in flounder (Pleuronectes flesus L.) erythrocytes, where GABA may participate in the maintenance of a steady cell volume during changes in plasma osmolality2,3.
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FUGELLI, K., STORM-MATHISEN, J. & FONNUM, F. Synthesis of γ-Aminobutyric Acid in Fish Erythrocytes. Nature 228, 1001 (1970). https://doi.org/10.1038/2281001a0
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DOI: https://doi.org/10.1038/2281001a0
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