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Isolation of an E. coli Strain with a Mutation affecting DNA Polymerase

Abstract

By testing indiscriminately several thousand colonies of mutagenized E. coli, a mutant has been isolated that on extraction proves to have less than I per cent of the normal level of DNA polymerase. The mutant multiplies normally but has acquired an increased sensitivity to ultraviolet light.

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DE LUCIA, P., CAIRNS, J. Isolation of an E. coli Strain with a Mutation affecting DNA Polymerase. Nature 224, 1164–1166 (1969). https://doi.org/10.1038/2241164a0

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