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High Resolution Nuclear Magnetic Resonance Studies of Biopolymers

Nature volume 220, pages 1079–1084 (1968)Cite this article

Abstract

Nuclear magnetic resonance at very high field strengths can give a wealth of information about macromolecules, though there are still limitations to the size of globular protein which it can handle.

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References

  1. Pople, J. A., Schneider, W. G., and Bernstein, H. J., High Resolution Nuclear Magnetic Resonance (McGraw-Hill, 1959).

    Google Scholar 

  2. Emsley, J. W., Feeney, J., and Sutcliffe, L. H., High Resolution Nuclear Magnetic Resonance Spectroscopy, 1, 2 (Pergamon, 1965).

    Google Scholar 

  3. Kowalsky, A., and Cohn, M., Ann. Rev. Biochem., 33, 481 (1964).

    Article  CAS  Google Scholar 

  4. Jardetzky, O., and Jardetzky, C. D., Methods in Biochemical Analysis (edit. by Glick, D.), 9 (Interscience, 1962).

    MATH  Google Scholar 

  5. Jardetzky, O., Adv. Chem. Physics, 7, 499 (1964).

    Google Scholar 

  6. McDonald, C. C., Phillips, W. D., and Lazar, J., J. Amer. Chem. Soc., 89, 4166 (1967).

    Article  CAS  Google Scholar 

  7. McDonald, C. C., and Phillips, W. D., J. Amer. Chem. Soc., 89, 6332 (1967).

    Article  CAS  Google Scholar 

  8. Marlborough, D. I., Orrell, K. G., and Rydon, H. N., Chem. Commun., 518 (1965).

  9. Bovey, F. A., and Tiers, G. V. D., J. Amer. Chem. Soc., 81, 2870 (1959).

    Article  CAS  Google Scholar 

  10. Meadows, D. H., Markley, J. L., Cohen, J. S., and Jardetzky, O., Proc. US Nat. Acad. Sci., 58, 1307 (1967).

    Article  ADS  CAS  Google Scholar 

  11. Markley, J. L., Meadows, D. H., and Jardetzky, O., J. Mol. Biol., 27, 25 (1967).

    Article  CAS  Google Scholar 

  12. Stewart, W. E., Mandelkern, L., and Glick, R. E., Biochemistry, 6, 143 (1967).

    Article  CAS  Google Scholar 

  13. Bradbury, E. M., Crane-Robinson, C., and Rattle, H. W. E., Nature, 216, 862 (1967).

    Article  ADS  CAS  Google Scholar 

  14. Bradbury, E. M., Crane-Robinson, C., Goldman, H., and Rattle, H. W. E., Nature, 217, 812 (1968).

    Article  ADS  CAS  Google Scholar 

  15. Ferretti, J. A., Chem. Commun., 1030 (1967).

  16. McTague, J. P., Ross, V., and Gibbs, J. H., Biopolymers, 2, 163 (1964).

    Article  CAS  Google Scholar 

  17. Jardetzky, O., First Biopolymers Symp., 501 (Interscience, 1964).

    Google Scholar 

  18. Bradbury, E. M., and Rattle, H. W. E., Polymer, 9, 201 (1968).

    Article  CAS  Google Scholar 

  19. Bradbury, E. M., Crane-Robinson, C., Goldman, H., and Rattle, H. W. E., Biopolymers, 6, 851 (1968).

    Article  CAS  Google Scholar 

  20. Bradbury, J. H., and Scheraga, H. A., J. Amer. Chem. Soc., 88, 4240 (1966).

    Article  CAS  Google Scholar 

  21. Bradbury, J. H., and Wilairat, P., Biochem. Biophys. Res. Commun., 29, 84 (1967).

    Article  CAS  Google Scholar 

  22. Kowalsky, A., J. Biol. Chem., 237, 1807 (1961).

    Google Scholar 

  23. Bradbury, E. M., Crane-Robinson, C., Goldman, H., Rattle, H. W. E., and Stephens, R. M., J. Mol. Biol., 29, 507 (1967).

    Article  CAS  Google Scholar 

  24. Hollis, D. P., McDonald, G., and Biltonen, R. C., Proc. US Nat. Acad. Sci., 58, 758 (1967).

    Article  ADS  CAS  Google Scholar 

  25. Sternlicht, H., and Wilson, D., Biochemistry, 6, 2881 (1967).

    Article  CAS  Google Scholar 

  26. Blake, C. C. F., Johnson, L. N., Mair, G. A., North, A. C. T., Phillips, D. C., and Sarma, V. R., Proc. Roy. Soc., 167, 378 (1967).

    Article  ADS  CAS  Google Scholar 

  27. McDonald, C. C., Phillips, W. D., and Penman, S., Science, 144, 1234 (1964).

    Article  ADS  CAS  Google Scholar 

  28. McDonald, C. C., Phillips, W. D., and Penswick, J., Biopolymers, 3, 609 (1965).

    Article  CAS  Google Scholar 

  29. Inoue, Y., and Nakanishi, K., Biochim. Biophys. Acta, 120, 311 (1966).

    Article  CAS  Google Scholar 

  30. Fischer, J. J., and Jardetzky, O., J. Amer. Chem. Soc., 87, 3237 (1965).

    Article  CAS  Google Scholar 

  31. Jardetzky, O., and Wade-Jardetzky, N. G., Mol. Pharmacol., 1, 214 (1965).

    PubMed  CAS  Google Scholar 

  32. Burgen, A. S. V., Jardetzky, O., Metcalfe, J. C., and Wade-Jardetzky, N. G., Proc. US Nat. Acad. Sci., 58, 447 (1967).

    Article  ADS  CAS  Google Scholar 

  33. Jardetzky, O., Wade-Jardetzky, N. G., and Fischer, J. J., Nature, 197, 183 (1963).

    Article  ADS  CAS  Google Scholar 

  34. Hollis, D. P., Bolen, J. R., and Kellum, J. M., Biochem. Biophys. Res. Commun., 22, 135 (1966).

    Article  CAS  Google Scholar 

  35. Hollis, D. P., in Magnetic Resonance in Biology (edit. by Malstrom, B. G., and Vanngard, T.) (Pergamon, Oxford, 1967).

    Google Scholar 

  36. Inoue, Y., and Inoue, S., Biochim. Biophys. Acta, 128, 100 (1966).

    Article  CAS  Google Scholar 

  37. Ferguson, R. C., and Phillips, W. D., Science, 157, 257 (1967).

    Article  ADS  CAS  Google Scholar 

  38. Navon, G., Shulman, R. G., Wyluda, B. J., and Yamane, T., Proc. US Nat. Acad. Sci., 60, 86 (1968).

    Article  ADS  CAS  Google Scholar 

  39. Cohen, J. S., and Jardetzky, O., Proc. US Nat. Acad. Sci., 60, 92 (1968).

    Article  ADS  CAS  Google Scholar 

  40. Gerig, J. T., J. Amer. Chem. Soc., 90, 2681 (1968).

    Article  CAS  Google Scholar 

  41. Bradbury, E. M., Carpenter, B. G., Crane-Robinson, C., and Rattle, H. W. E., Nature, 220, 69 (1968).

    Article  ADS  CAS  Google Scholar 

  42. Smith, I. C., Yamane, T., and Shulman, R. G., Science, 159, 1360 (1968).

    Article  ADS  CAS  Google Scholar 

  43. Kowalsky, A., Biochemistry, 4, 2382 (1965).

    Article  CAS  Google Scholar 

  44. Wüthrich, K., Shulman, R. G., and Peisach, J., Proc. US Nat. Acad. Sci., 60, 373 (1968).

    Article  ADS  Google Scholar 

  45. Jardetzky, O., Proc. Intern. Symp. Nuclear Magnetic Resonance, Tokyo, Japan, N-3-14 (1965).

  46. Markley, J. L., Putter, I., and Jardetzky, O., Science, 161, 1249 (1968).

    Article  ADS  CAS  Google Scholar 

  47. Crespi, H. L., Rosenberg, R. M., and Katz, J. C., Science, 161, 795 (1968).

    Article  ADS  CAS  Google Scholar 

  48. Bovey, F. A., J. Pure Appl. Chem., 2, 417 (1968).

    Google Scholar 

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Authors and Affiliations

  1. College of Technology, Portsmouth

    E. M. BRADBURY & C. CRANE-ROBINSON

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  1. E. M. BRADBURY
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  2. C. CRANE-ROBINSON
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BRADBURY, E., CRANE-ROBINSON, C. High Resolution Nuclear Magnetic Resonance Studies of Biopolymers. Nature 220, 1079–1084 (1968). https://doi.org/10.1038/2201079a0

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