Abstract
SEVERAL treatments which increase the concentration of ionized calcium in the plasma of the rat have been shown to increase the rate at which thymus and bone marrow cells enter mitosis1–3. Because the calcium concentration in the blood is controlled by two mutually antagonistic hormones, parathyroid hormone and calcitonin4–6, then mitosis in bone marrow and thymus may be subject to control by these hormones. It has not been established, however, whether any hormonally mediated calcium shifts are important in physiological fluctuations in the rate of cell division in these tissues.
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PERRIS, A., WHITFIELD, J. & TÖLG, P. Role of Calcium in the Control of Growth and Cell Division. Nature 219, 527–529 (1968). https://doi.org/10.1038/219527a0
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DOI: https://doi.org/10.1038/219527a0
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