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Influence of Oxygen and Cysteine on the Radical State of X-irradiated Lyophilized Liver

Abstract

Blyumenfel'd and Kalmanson1 as well as Gordy2 and Miyagawa3 have already reported that radicals are formed in lyophilized rat liver by ionizing radiation using electron spin resonance techniques. Moreover, Gordy and Miyagawa have shown that oxygen and cysteine, which was allowed to diffuse into the liver before freeze-drying, alter the electron spin resonance spectra. This report describes investigations on X-irradiated mouse liver. The study also includes preparations of liver in which solutions of cysteine were injected before freeze-dry ing. To some extent we obtained results different from those described by the foregoing authors.

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References

  1. Blyumenfel'd, L. A., and Kalmanson, A. E., Biofizika, 2, 552 (1957).

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  2. Gordy, W., Rad. Res., Suppl. 1, 491 (1959).

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ABE, M., MÖNIG, H. & KOCH, R. Influence of Oxygen and Cysteine on the Radical State of X-irradiated Lyophilized Liver. Nature 208, 499–500 (1965). https://doi.org/10.1038/208499a0

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  • DOI: https://doi.org/10.1038/208499a0

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